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ACC-789

ACC-789

Item no.	V3414-100mg
Manufacturer	InvivoChem LLC
CASRN	300842-64-2
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3414CAS #:300842-64-2Purity >=98% Description: ACC-789, also known as ZK-202650 and NVP-ACC789 is a novel, potent, selective and orally bioavailable inhibitor of human VEGFR-1, VEGFR-2 (mouse VEGFR-2), VEGFR-3 and PDGFR-beta with IC50s of 0.38, 0.02 (0.23), 0.18, 1.4 uM, respectively. Exponential tumor growth is angiogenesis-dependent. Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) are potent angiogenic inducers that act synergistically in vivo and in vitro. References: J Pharmacol Exp Ther. 2001 Dec; 299(3):1073-85.
	Name: ACC-789 CAS#: 300842-64-2 Chemical Formula: C21H17BrN4 Exact Mass: 404.0637 Molecular Weight: 405.299 Elemental Analysis: C, 62.23; H, 4.23; Br, 19.71; N, 13.82
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: ZK-202650; ZK 202650; ZK202650; NVP-ACC789; NVP-ACC 789; NVP-ACC-789; ACC-789; ACC 789; ACC789. Chemical Name: N-(3-Bromo-4-methylphenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine InChi Key: GXWKSXUPEFVUOO-UHFFFAOYSA-N InChi Code: InChI=1S/C21H17BrN4/c1-14-6-7-16(13-19(14)22)24-21-18-5-3-2-4-17(18)20(25-26-21)12-15-8-10-23-11-9-15/h2-11, 13H, 12H2, 1H3, (H, 24, 26) SMILES Code: CC1=CC=C(NC2=NN=C(CC3=CC=NC=C3)C4=C2C=CC=C4)C=C1Br

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 11/6/2025

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