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kb NB 142-70

kb NB 142-70

Item no.	V3422-500mg
Manufacturer	InvivoChem LLC
CASRN	1233533-04-4
Amount	500 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3422CAS #:1233533-04-4 Purity >=98% Description: kb NB 142-70 is a novel, potent and selective PKD (protein kinase D) inhibitor with IC50s of 28.3, 58.7 and 53.2 nM for PKD1, PKD2, and PKD3, respectively. kb NB 142-70 has potential antitumor activity. Protein kinase D (PKD) has been implicated in a wide range of cellular processes and pathological conditions including cancer. However, targeting PKD therapeutically and dissecting PKD-mediated cellular responses remains difficult due to lack of a potent and selective inhibitor. kb NB 142-70 prevents wound-induced migration of intestinal epithelial cells. References: BMC Chem Biol. 2010 May 5; 10:5. doi: 10.1186/1472-6769-10-5; Am J Physiol Cell Physiol. 2014 May 15; 306(10):C961-71.
	Name: kb NB 142-70 CAS#: 1233533-04-4 Chemical Formula: C11H9NO2S2 Exact Mass: 251.00747 Molecular Weight: 251.32 Elemental Analysis: C, 52.57; H, 3.61; N, 5.57; O, 12.73; S, 25.51
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: kb NB 142-70; kb NB142-70; kb NB-142-70; kb NB 142-70; kb NB 142 70; . Chemical Name: 9-hydroxy-3, 4-dihydrobenzo[4, 5]thieno[2, 3-f][1, 4]thiazepin-5(2H)-one InChi Key: DHUAGGSHTKPOHU-UHFFFAOYSA-N InChi Code: InChI=1S/C11H9NO2S2/c13-6-1-2-8-7(5-6)9-10(16-8)11(14)12-3-4-15-9/h1-2, 5, 13H, 3-4H2, (H, 12, 14) SMILES Code: O=C1NCCSC2=C1SC3=CC=C(O)C=C32

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 mg

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Delivery expected until 9/4/2025

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