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BRD9539

BRD9539

Item no.	V3455-10mg
Manufacturer	InvivoChem LLC
CASRN	1374601-41-8
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3455CAS #:1374601-41-8 Purity >=98% Description: BRD9539 is a potent and selective inhibitor that inhibits G9a activity with an IC50 of 6.3 uM, it also inhibits euchromatin histone methyltransferase 2 (EHMT2). Post-translational modifications of histones alter chromatin structure and play key roles in gene expression and specification of cell states. Small molecules that target chromatin-modifying enzymes selectively are useful as probes and have promise as therapeutics, although very few are currently available. G9a (also named euchromatin histone methyltransferase 2 (EHMT2)) catalyzes methylation of lysine 9 on histone H3 (H3K9), a modification linked to aberrant silencing of tumor-suppressor genes, among others. References: ACS Chem Biol. 2012 Jul 20; 7(7):1152-7.
	Name: BRD9539 CAS#: 1374601-41-8 Chemical Formula: C24H21N3O3 Exact Mass: 399.1583 Molecular Weight: 399.45 Elemental Analysis: C, 72.17; H, 5.30; N, 10.52; O, 12.02
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: BRD9539; BRD 9539; BRD-9539. Chemical Name: 2-benzamido-1-(3-phenylpropyl)-1H-1, 3-benzodiazole-5-carboxylic acid InChi Key: WPXMEOBILYVKBC-UHFFFAOYSA-N InChi Code: InChI=1S/C24H21N3O3/c28-22(18-11-5-2-6-12-18)26-24-25-20-16-19(23(29)30)13-14-21(20)27(24)15-7-10-17-8-3-1-4-9-17/h1-6, 8-9, 11-14, 16H, 7, 10, 15H2, (H, 29, 30)(H, 25, 26, 28) SMILES Code: O=C(C1=CC=C(N(CCCC2=CC=CC=C2)C(NC(C3=CC=CC=C3)=O)=N4)C4=C1)O

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Amount: 10 mg

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Delivery expected until 10/2/2025

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