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Entecavir (SQ 34676)

Entecavir (SQ 34676)

Item no.	V3511-250mg
Manufacturer	InvivoChem LLC
CASRN	142217-69-4
Amount	250 mg
Quantity options	100 mg 10 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3511CAS #:142217-69-4 (free); 209216-23-9 (hydrate); 911138-73-3 (maleate) Purity >=98% Description: Entecavir (also known as SQ 34676 and BMS 200475), anti-hepatitis B virus (HBV) agent, is a novel deoxyguanine nucleosideanalogue and a reverse transcriptase inhibitor. Entecavir is a potentand selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cells.It is an oral antiviral drug used in the treatment of hepatitis B virus(HBV) infection. It prevents the hepatitis B virus from multiplying andreduces the amount of virus in the body. Entecavir is a highly potentinhibitor of wild-type HBV Pol and is 100- to 300-fold more potent thanlamivudine-triphosphate against 3TC-resistant HBV Pol. Entecavirinhibits the replication of 3TC-resistant HBV, but 20- to 30-fold higherconcentrations are required. , anti-hepatitis B virus (HBV) agent, is a novel deoxyguanine nucleosideanalogue and a reverse transcriptase inhibitor. Entecavir is a potentand selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cells.It is an oral antiviral drug used in the treatment of hepatitis B virus(HBV) infection. It prevents the hepatitis B virus from multiplying andreduces the amount of virus in the body. Entecavir is a highly potentinhibitor of wild-type HBV Pol and is 100- to 300-fold more potent thanlamivudine-triphosphate against 3TC-resistant HBV Pol. Entecavirinhibits the replication of 3TC-resistant HBV, but 20- to 30-fold higherconcentrations are required. References: Antimicrob Agents Chemother. 2002 Aug; 46(8):2525-32; Antimicrob Agents Chemother. 2003 Aug; 47(8):2624-35. Related CAS#: 142217-69-4 (free); 911138-73-3 (maleate); 209216-23-9 (hydrate)
Molecular Weight (MW)	277.28
Formula	C12H15N5O3
CAS No.	209216-23-9 (hydrate); 142217-69-4 (free); 911138-73-3 (maleate)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 40 mg/mL
	Water:< 1 mg/mL
	Ethanol:< 1 mg/mL
SMILES	O=C1NC(N)=NC2=C1N=CN2[CH]3C([CH](CO)[CH](O)C3)=C.[H]O[H]
Synonyms	BMS-200475; BMS 200475; BMS200475; BMS 200475-01; BMS-200475-01; Entecavir monohydrate; Baraclude; D07896

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 9/4/2025

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