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Pexacerfont

Pexacerfont

Item no.	V3522-10mg
Manufacturer	InvivoChem LLC
CASRN	459856-18-9
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3522CAS #:459856-18-9Purity >=98% Description: Pexacerfont (formerly known as BMS-562086) is a novel potent, selective and orally bioactive antagonist of corticotropin-releasing factor (CRF1) receptor antagonist with IC50 of 6.1+/-0.6 nM for human CRF1 receptor. Pexacerfont is currently in clinical trials for the treatment of anxiety disorders, and has also been proposed to be useful for the treatment of depression and irritable bowel syndrome. BMS-562086 exhibited favorable ADME and pharmacokinetic properties for further development. References: Drug Metab Dispos. 2012 Jun; 40(6):1093-103.
	Name: Pexacerfont CAS#: 459856-18-9 Chemical Formula: C18H24N6O Exact Mass: 340.2012 Molecular Weight: 340.431 Elemental Analysis: C, 63.51; H, 7.11; N, 24.69; O, 4.70
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: BMS-562086; BMS 562086; BMS562086; BMS-562, 086; BMS562, 086; BMS 562, 086 Chemical Name: 8-(6-Methoxy-2-methylpyridin-3-yl)-2, 7-dimethyl-N-((1R)-1-methylpropyl)pyrazolo(1, 5-a)-1, 3, 5-triazin-4-amine InChi Key: LBWQSAZEYIZZCE-SNVBAGLBSA-N InChi Code: InChI=1S/C18H24N6O/c1-7-10(2)19-18-22-13(5)21-17-16(12(4)23-24(17)18)14-8-9-15(25-6)20-11(14)3/h8-10H, 7H2, 1-6H3, (H, 19, 21, 22)/t10-/m1/s1 SMILES Code: CC[CH](NC1=NC(C)=NC2=C(C3=CC=C(OC)N=C3C)C(C)=NN21)C

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Amount: 10 mg

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Delivery expected until 9/4/2025

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