AT6

Item no.	V3582-50mg
Manufacturer	InvivoChem LLC
CASRN	2098836-50-9
Amount	50 mg
Quantity options	10 mg 25 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3582CAS #:2098836-50-9Purity >=98% Description: AT6 is a novel, potent and highly selective PROTAC-based BRD degrader, it is analog of AT1. Inducing macromolecular interactions with small molecules to activate cellular signaling is a challenging goal. PROTACs (proteolysis-targeting chimeras) are bifunctional molecules that recruit a target protein in proximity to an E3 ubiquitin ligase to trigger protein degradation. Structural elucidation of the key ternary ligase-PROTAC-target species and its impact on target degradation selectivity remain elusive. References: Nat Chem Biol. 2017 May; 13(5):514-521.
	Molecular Weight: 1004.68 Formula: C??H??ClN?O?S? CAS No.: 2098836-50-9 SMILES: CC1=C(C)C(C(C2=CC=C(Cl)C=C2)=N[CH](CC(NCCOCCOCCSC(C)(C)[CH](NC(C)=O)C(N3C[CH](O)C[CH]3C(NCC4=CC=C(C5=C(C)N=CS5)C=C4)=O)=O)=O)C6=NN=C(C)N67)=C7S1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	AT6; AT-6; AT 6

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Amount: 50 mg

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