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Epetraborole hydrochloride

Epetraborole hydrochloride

Item no.	V3637-50mg
Manufacturer	InvivoChem LLC
CASRN	1234563-16-6
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3637CAS #:1234563-16-6 Purity >=98% Description: Epetraborole hydrochloride (also known as GSK2251052 hydrochloride and AN3365 hydrochloride) is a novel, potent and selective leucyl-tRNA synthetase (LeuRS) inhibitor, which inhibits protein synthesis by binding to the terminal adenosine ribose (A76) of leucyl-tRNA synthetase. Epetraborole was under investigation for the treatment of infections caused by multidrug-resistant Gram-negative pathogens. GSK2251052 is a novel boron-containing antibiotic that inhibits bacterial leucyl tRNA synthetase. All Clostridium perfringens strains had GSK2251052 MICs of > 32 ug/ml. References: Antimicrob Agents Chemother. 2013 May; 57(5):2401-4.; Antimicrob Agents Chemother. 2015 Jan; 59(1):289-98 Related CAS#:1093643-37-8 (free base); 1234563-15-5 (R-mandelate)
	Name: Epetraborole HCl CAS#: 1234563-16-6 (HCl) Chemical Formula: C11H17BClNO4 Exact Mass: 237.1172 Molecular Weight: 273.52 Elemental Analysis: C, 48.30; H, 6.26; B, 3.95; Cl, 12.96; N, 5.12; O, 23.401
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: GSK-2251052; GSK 2251052; GSK2251052; AN3365; AN 3365; AN-3365; GSK-052; GSK 052; GSK052; Epetraborole Chemical Name: (S)-3-(Aminomethyl)-7-(3-hydroxypropoxy)-1-hydroxy-1, 3-dihydro-2, 1-benzoxaborole hydrochloride InChi Key: DADYQGIQOBJGIW-HNCPQSOCSA-N InChi Code: InChI=1S/C11H16BNO4.ClH/c13-7-10-8-3-1-4-9(16-6-2-5-14)11(8)12(15)17-10; /h1, 3-4, 10, 14-15H, 2, 5-7, 13H2; 1H/t10-; /m1./s1 SMILES Code: OB1O[CH](CN)C2=CC=CC(OCCCO)=C21.[H]Cl

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Amount: 50 mg

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Delivery expected until 10/2/2025

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