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Toceranib

Toceranib

Item no.	V3698-500mg
Manufacturer	InvivoChem LLC
CASRN	356068-94-5
Amount	500 mg
Quantity options	100 mg 1 g 250 mg 2 g 50 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3698CAS #:356068-94-5 Purity >=98% Description: Toceranib (formerly known as PHA-291639, or SU 11654) is an inhibitor of receptor tyrosine kinase (RTK) with Ki values of 6 nM and 5 nM for Flk-1/KDR and PDGFRbeta, respectively. It is used in the treatment of canine mast cell tumor (also called mastocytoma). Toceranib is an veterinary drug that was approved for use in dog. Toceranib is likely to act mostly through inhibition of the kit tyrosine kinase, though it may also have an anti-angiogenic effect. References: J Vet Intern Med. 2012 Mar-Apr; 26(2):355-62; BMC Vet Res. 2014 May 6; 10:105. Related CAS#:874819-74-6 (phosphate)
Molecular Weight (MW)	396.47
Formula	C22H25FN4O2
CAS No.	356068-94-5 (free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mM
	Water: < 1mg/mL
	Ethanol: < 1mg/mL
Chemical Name	(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2, 4-dimethyl-N-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrrole-3-carboxamide
Synonyms	SU-11654; SU 11654; SU11654; PHA-291639; PHA291639; PHA 291639; Toceranib; Trade name: Palladia.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 mg

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