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Description: Tizoxanide, a thiazolide anti-infective, is an active metabolite of Nitazoxanide (also known as NTZ; NSC 697855), which is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent with IC50 for canine influenza virus ranges from 0.17 to 0.21 uM. Tizoxanide is active against anaerobic bacteria, protozoa, and a range of viruses in cell culture models, and is currently in phase II clinical development for treating chronic hepatitis C.
References: Antimicrob Agents Chemother. 1998 Aug; 42(8):1959-65; Clin Infect Dis. 2005 Apr 15; 40(8):1173-80.
Related CAS#:1246819-17-9 (Nitazoxanide D4); 55981-09-4 (Nitazoxanide)
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