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haemanthamine-hcl

haemanthamine-hcl

Item no.	V38784-50mg
Manufacturer	InvivoChem LLC
CASRN	466-75-1 (free base)
Amount	50 mg
Quantity options	100 mg 1 g 250 mg 500 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V38784CAS #:466-75-1 (free base)Purity >=98% Description: Haemanthamine HCl is a naturally occuring crinine-type alkaloid extracted from the Amaryllidaceae plants with highly potent anticancer activity. Haemanthamine HCl targets ribosomal that inhibits protein biosynthesis during the elongation stage of translation. Haemanthamine HCl has pro-apoptotic, antioxidant, antiviral, antimalarial and anticonvulsant activities. References: 1. PellegrinoS, et al. The Amaryllidaceae Alkaloid Haemanthamine Binds theEukaryotic Ribosome to Repress Cancer Cell Growth. Structure. 2018 Mar6; 26(3):416-425.e4. 2. SeifrtovaM, et al. Haemanthamine alters sodium butyrate-induced histoneacetylation, p21WAF1/Cip1 expression, Chk1 and Chk2 activation and leadsto increased growth inhibition and death in A2780 ovarian cancer cells.Phytomedicine. 2017 Nov 15; 35:1-10.

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Amount: 50 mg

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