Comparison

ARS-1620

Item no. V3974-100mg
Manufacturer InvivoChem LLC
CASRN 1698055-85-4
Amount 100 mg
Quantity options 10 mg 1 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V3974CAS #:1698055-85-4Purity >=98%

Description: ARS-1620 is a novel, potent, orally bioavailable and covalent inhibitor of KRASG12C with antitumor activity. It has high potency and selectivity for KRASG12C. ARS-1620 is a new generation of KRASG12C-specific inhibitors with promising therapeutic potential.

References: 2018 Jan 25; 172(3):578-589.e17.

Publications Citing Use of InvivoChem ARS-1620: Bioorg Chem. 2021 May; 110:104825. doi: 10.1016/j.bioorg.2021.104825.

Molecular Weight (MW)
430.84
Formula
C21H17ClF2N4O2
CAS No.
1698055-85-4
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: >= 80 mg/mL
Water: < 1 mg/mL
Ethanol: >= 30 mg/mL
Chemical Name
(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
Synonyms
ARS 1620; ARS1620; ARS-1620;

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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