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bay-1797

bay-1797

Item no.	V40279-250mg
Manufacturer	InvivoChem LLC
CASRN	2055602-83-8
Amount	250 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V40279CAS #:2055602-83-8Purity >=98% Description: BAY-1797 is a highly potent, orally bioavailable, and specific P2X4 antagonist with an IC50 of 211 nM against human P2X4. BAY-1797 displays no or very weak activity on the other P2X ion channels. BAY-1797 shows anti-nociceptive and anti-inflammatory effects. Theanti-inflammatory and anti-nociceptive effects of BAY-1797 weredemonstrated in a mouse complete Freund's adjuvant (CFA) inflammatorypain model. References: Discoveryand Characterization of the Potent and Selective P2X4 InhibitorN-4-(3-Chlorophenoxy)-3-sulfamoylphenyl-2-phenylacetamide (BAY-1797)and Structure-Guided Amelioration of Its CYP3A4 Induction Profile. J MedChem. 2019 Dec 26; 62(24):11194-11217.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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