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Roquinimex

Roquinimex

Item no.	V4039-10mg
Manufacturer	InvivoChem LLC
CASRN	84088-42-6
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4039CAS #:84088-42-6Purity >=98% Description: Roquinimex (also known as LS 2616 and FCF89; trade name: Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity. It also inhibits angiogenesis and reduces the secretion of TNF alpha. Roquinimex has been investigated as a treatment for some cancers (including as adjuvant therapy after bone marrow transplantation in acute leukemia) and autoimmune diseases, such as multiple sclerosis and recent-onset type I diabetes. Several trials have been terminated due to serious cardiovascular toxicity. Description: References: Inflamm Res. 2003 Feb; 52(2):64-8; Acta Neurol Scand. 1998 Aug; 98(2):94-101. References:
Molecular Weight (MW)	308.33
Formula	C18H16N2O3
CAS No.	84088-42-6
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: >= 80mg/mL
	Water: N/A
	Ethanol: N/A
Chemical Name	4-hydroxy-N, 1-dimethyl-2-oxo-N-phenyl-1, 2-dihydroquinoline-3-carboxamide
Synonyms	LS2616; LS2616; LS 2616; FCF89; FCF89; FCF 89; Linomide. Trade name: Linomide
SMILES Code	O=C(C1=C(O)C2=C(N(C)C1=O)C=CC=C2)N(C)C3=CC=CC=C3

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Amount: 10 mg

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