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SRT1720

SRT1720

Item no.	V4054-100mg
Manufacturer	InvivoChem LLC
CASRN	925434-55-5
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4054CAS #:925434-55-5 Purity >=98% Description: SRT1720 (formerly known as CAY10559) is a novel and selective SIRT1 activator with an EC50 of 0.16 uM in a cell-free assay, but is > 230-fold less potent for SIRT2 and SIRT3. It shows similar activity with the known SIRT1 activator resveratrol, but is 1000-fold more potent. In animal studies it was found to improve insulin sensitivity and lower plasma glucose levels in fat, muscle and liver tissue, and increased mitochondrial and metabolic function. A study of SRT1720 conducted by the National Institute on Aging found that the drug may extend the lifespan of obese mice by 44%. Description: References: Nature. 2007 Nov 29; 450(7170):712-6; Br J Haematol. 2011 Dec; 155(5):588-98. References: Related CAS#:1001645-58-4 (HCl salt)
Molecular Weight (MW)	469.56
Formula	C25H23N7OS
CAS No.	925434-55-5 (free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mM
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	N/A
Synonyms	CAY-10559; CAY10559; CAY 10559; SRT-1720 HCl, SRT-1720; SRT1720; SRT-1720; SRT 1720; SIRT-1933; SIRT 1933; SIRT1933.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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