ODQ

Item no.	V4101-1g
Manufacturer	InvivoChem LLC
CASRN	41443-28-1
Amount	1 g
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4101CAS #:41443-28-1Purity >=98% Description: ODQ is a novel, potent and selective inhibitor of soluble guanylyl cyclase (sGC). The binding of ODQ is competitive with NO. Soluble guanylyl cyclase (sGC) is a receptor for nitric oxide that generates cGMP. This second messenger molecule has established roles in cellular physiology; however, less is known about its effects in tumour cells. The action of ODQ in LNCaP cells did not reflect sGC inhibition. ODQ promotes cell death and inhibits growth and migration of prostate cancer cells and that these actions are independent of its effects on GMP levels. Description: References: Br J Pharmacol. 2008 Nov; 155(6):804-13. References:
Molecular Weight (MW)	187.15
Formula	C9H5N3O2
CAS No.	41443-28-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mM
	Water: N/A
	Ethanol: N/A
Chemical Name	1H-[1, 2, 4]Oxadiazolo[4, 3-a]quinoxalin-1-one
Synonyms	ODQ
SMILES Code	O=C1ON=C2N1C3=C(C=CC=C3)N=C2

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