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BAY-677

BAY-677

Item no.	V4164-50mg
Manufacturer	InvivoChem LLC
CASRN	2117404-84-7
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4164CAS #:2117404-84-7Purity >=98% Description: BAY-677 is an inactive and negative control for BAY-678. BAY-678 is a novel, potent, orally bioavailable, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). Description: References: ChemMedChem. 2015 Jul; 10(7):1163-73.; Bioorg Med Chem Lett. 2015 Oct 15; 25(20):4370-81. References: Related CAS#:675103-36-3 (BAY-678); 675103-35-2 (BAY-678 racemate)
	Name: BAY-677 CAS#: 2117404-84-7 (BAY-677); Chemical Formula: C20H15F3N4O2 Exact Mass: 400.1147 Molecular Weight: 400.36 Elemental Analysis: C, 60.00; H, 3.78; F, 14.24; N, 13.99; O, 7.99
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: BAY-677; BAY 677; BAY677 IUPAC/Chemical Name: 5-[(4S)-5-Acetyl-1, 2, 3, 4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile InChi Key: PGIVGIFOWOVINL-SFHVURJKSA-N InChi Code: InChI=1S/C20H15F3N4O2/c1-11-17(12(2)28)18(13-6-7-15(9-24)25-10-13)26-19(29)27(11)16-5-3-4-14(8-16)20(21, 22)23/h3-8, 10, 18H, 1-2H3, (H, 26, 29)/t18-/m0/s1 SMILES Code: N#CC1=NC=C([CH](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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Delivery expected until 9/4/2025

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