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freselestat

freselestat

Item no.	V4184-50mg
Manufacturer	InvivoChem LLC
CASRN	208848-19-5
Amount	50 mg
Quantity options	100 mg 10 mg 25 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4184CAS #:208848-19-5 Purity >=98% Description: Freselestat (also known as ONO-6818) is a novel, potent and selective inhibitor of Human Neutrophil Elastase (HNE). Freselestat reduces inflammatory mediators during simulated extracorporeal circulation. ONO-6818 significantly reduced interleukin 8 and C5b-9 production. ONO-6818 did not modulate changes of CD11b and L-selectin during recirculation. Description: References: Ann Thorac Surg. 2003 Oct; 76(4):1234-9. References:
	Name: Freselestat CAS#: 208848-19-5 Chemical Formula: C23H28N6O4 Exact Mass: 452.2172 Molecular Weight: 452.515 Elemental Analysis: C, 61.05; H, 6.24; N, 18.57; O, 14.14
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: ONO-6818; ONO6818; ONO 6818; ONO-PO 736; ONO-PO-736; ONO PO 736; IUPAC/Chemical Name: 2-(5-amino-6-oxo-2-phenylpyrimidin-1(6H)-yl)-N-(1-(5-(tert-butyl)-1, 3, 4-oxadiazol-2-yl)-3-methyl-1-oxobutan-2-yl)acetamide InChi Key: YSIHYROEMJSOAS-UHFFFAOYSA-N InChi Code: InChI=1S/C23H28N6O4/c1-13(2)17(18(31)20-27-28-22(33-20)23(3, 4)5)26-16(30)12-29-19(14-9-7-6-8-10-14)25-11-15(24)21(29)32/h6-11, 13, 17H, 12, 24H2, 1-5H3, (H, 26, 30) SMILES Code: O=C(NC(C(C1=NN=C(C(C)(C)C)O1)=O)C(C)C)CN(C(C2=CC=CC=C2)=NC=C3N)C3=O

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Amount: 50 mg

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Delivery expected until 10/2/2025

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