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Vericiguat

Vericiguat

Item no.	V4207-500mg
Manufacturer	InvivoChem LLC
CASRN	1350653-20-1
Amount	500 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4207CAS #:1350653-20-1Purity >=98% Description: Vericiguat (also known as BAY1021189 and BAY10-21189) is a novel, potent, orally bioavailable and soluble guanylate cyclase (sGC) stimulator. The first-in-class soluble guanylate cyclase (sGC) stimulator riociguat was recently introduced as a novel treatment option for pulmonary hypertension. Despite its outstanding pharmacological profile, application of riociguat in other cardiovascular indications is limited by its short half-life, necessitating a three times daily dosing regimen. Vericiguat is currently in phase 3 trials for chronic heart failure. Description: References: J Med Chem. 2017 Jun 22; 60(12):5146-5161. References:
	Name: Vericiguat CAS#: 1350653-20-1 Chemical Formula: C19H16F2N8O2 Exact Mass: 426.1364 Molecular Weight: 426.3878 Elemental Analysis: C, 53.52; H, 3.78; F, 8.91; N, 26.28; O, 7.50
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: BAY1021189; BAY 1021189; BAY-1021189; BAY10-21189; BAY-10-21189; BAY 10-21189. IUPAC/Chemical Name: methyl (4, 6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3, 4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate InChi Key: QZFHIXARHDBPBY-UHFFFAOYSA-N InChi Code: InChI=1S/C19H16F2N8O2/c1-31-19(30)25-14-15(22)26-17(27-16(14)23)13-11-6-10(20)7-24-18(11)29(28-13)8-9-4-2-3-5-12(9)21/h2-7H, 8H2, 1H3, (H, 25, 30)(H4, 22, 23, 26, 27) SMILES Code: O=C(OC)NC1=C(N)N=C(C2=NN(CC3=CC=CC=C3F)C4=NC=C(F)C=C42)N=C1N

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Amount: 500 mg

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Delivery expected until 9/4/2025

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