Comparison

AZD7507

Item no. V4238-10mg
Manufacturer InvivoChem LLC
CASRN 1041852-85-0
Amount 10 mg
Quantity options 100 mg 250 mg 25 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V4238CAS #:1041852-85-0 Purity >=98%

Description: AZD7507 is a novel, potent, selective and orally bioactive 3-amido-4-anilinoquinoline CSF-1R inhibitor with 32 nM cell activity and with antitumor activity. AZD7507 is considered to be a promising compound as it retained the desired potency and oral pharmacokinetic properties of AZ683. Moreover, in a telemetry study in dogs given a single oral dose, there was no cardiovascular toxicity, no elevation of troponin related to the treatment, and no alteration in the ECG.

Description:

References: Bioorg Med Chem Lett. 2013 Aug 15; 23(16):4591-6.; J Clin Invest. 2015 Mar 2; 125(3):1269-85.

References:


AZD7507

Name: AZD7507
CAS#: 1041852-85-0
Chemical Formula: C23H27FN6O3
Exact Mass: 454.2129
Molecular Weight: 454.5064
Elemental Analysis: C, 60.78; H, 5.99; F, 4.18; N, 18.49; O, 10.56
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Technical Information
Synonym: AZD7507; AZD-7507; AZD 7507.
IUPAC/Chemical Name: 4-(2-fluoro-4-methylanilino)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamide
InChi Key: CPDGCAFPSYOTGO-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H27FN6O3/c1-14-3-4-17(16(24)11-14)26-21-15-12-19(30-7-5-29(6-8-30)9-10-31)20(33-2)13-18(15)27-28-22(21)23(25)32/h3-4, 11-13, 31H, 5-10H2, 1-2H3, (H2, 25, 32)(H, 26, 27)
SMILES Code: O=C(C1=NN=C2C=C(OC)C(N3CCN(CCO)CC3)=CC2=C1NC4=CC=C(C)C=C4F)N

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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