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AZD9567

AZD9567

Item no.	V4259-10mg
Manufacturer	InvivoChem LLC
CASRN	1893415-00-3
Amount	10 mg
Quantity options	100 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4259CAS #:1893415-00-3 Purity >=98% Description: AZD9567 is a novel, potent, oral bioactive, non-steroidal and selective glucocorticoid receptor modulator (SGRM) with an IC50 of 3.8 nM. AZD9567 has excellent in vivo efficacy when dosed orally in a rat model of joint inflammation. AZD9567 exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation. It is currently being evaluated in clinical trials comparing the efficacy and side effect markers with those of prednisolone. Description: References: J Med Chem. 2018 Mar 8; 61(5):1785-1799. References:
	Name: AZD9567 CAS#: 1893415-00-3 Chemical Formula: C27H28F2N4O3 Exact Mass: 494.2129 Molecular Weight: 494.54 Elemental Analysis: C, 65.58; H, 5.71; F, 7.68; N, 11.33; O, 9.71
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: AZD9567; AZD-9567; AZD 9567 IUPAC/Chemical Name: 2, 2-Difluoro-N-[(1R, 2S)-3-methyl-1-[[1-(1-methyl-6-oxo-1, 6-dihydropyridin-3-yl)-1H-indazol-5-yl]oxy]-1-phenylbutan-2-yl]propanamide InChi Key: ZQFNDBISEYQVRR-LOSJGSFVSA-N InChi Code: InChI=1S/C27H28F2N4O3/c1-17(2)24(31-26(35)27(3, 28)29)25(18-8-6-5-7-9-18)36-21-11-12-22-19(14-21)15-30-33(22)20-10-13-23(34)32(4)16-20/h5-17, 24-25H, 1-4H3, (H, 31, 35)/t24-, 25+/m0/s1 SMILES Code: CC(F)(F)C(N[CH](C(C)C)[CH](OC1=CC2=C(N(C(C=C3)=CN(C)C3=O)N=C2)C=C1)C4=CC=CC=C4)=O

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Amount: 10 mg

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Delivery expected until 10/2/2025

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