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Description: TRi-1 (also know nas TXNRD1 inhibitor 1) is a novel, potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1) with anticancer potential activity. It showed 5- to 10-fold higher specificity for TXNRD1 over TXNRD2.
References: Sci Transl Med. 2018 Feb 14; 10(428). pii: eaaf7444.
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