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MK-6240

MK-6240

Item no.	V4291-50mg
Manufacturer	InvivoChem LLC
CASRN	1841078-87-2
Amount	50 mg
Quantity options	100 mg 10 mg 25 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4291CAS #:1841078-87-2Purity >=98% Description: MK-6240 is a novel positron emission tomography (PET) tracer for detecting neurofibrillary tangles (NFTs). It exhibits high specificity and selectivity for binding to NFTs. Neurofibrillary tangles (NFTs) made up of aggregated tau protein have been identified as the pathologic hallmark of several neurodegenerative diseases including Alzheimer's disease. In vivo detection of NFTs using PET imaging represents a unique opportunity to develop a pharmacodynamic tool to accelerate the discovery of new disease modifying therapeutics targeting tau pathology. MK-6240 demonstrates suitable physicochemical properties and in vivo pharmacokinetics. Description: References: J Med Chem. 2016 May 26; 59(10):4778-89. References:
	Molecular Weight: 278.28 Formula: C??H??FN? CAS No.: 1841078-87-2 SMILES: NC1=C(F)C=CC2=C1C=C(N3C=CC4=C3C=NC=C4)N=C2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	MK-6240; MK6240; MK 6240

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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Delivery expected until 10/2/2025

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