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Description: MK-2894 is a novel, potent and selective antagonist of prostaglandin E2 subtype 4 receptor (PGE2). MK-2894 demonstrates favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.
References: J Med Chem. 2010 Mar 11; 53(5):2227-38.
Related CAS#:1006036-88-9 (sodium)
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