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MK-3207

MK-3207

Item no.	V4317-500mg
Manufacturer	InvivoChem LLC
CASRN	957118-49-9
Amount	500 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4317CAS #:957118-49-9 (free base); Purity >=98% Description:MK-3207 is a novel, potent and orally bioactive CGRP (Calcitonin generelated peptide) receptor antagonist with IC50 and Kiof 0.12 nM and0.022 nM, it is highly selective versus human AM1, AM2, CTR, andAMY3. MK 3207 exhibits significantly higher affinity for both native andrecombinant human CGRP receptor, as well as rhesus monkey CGRP receptorwith Ki of 24 pM, ca.24 pM and 22 pM, respectively, as compared to CGRPreceptors from other species, including canine and rodent (Ki values ofca.10 nM). References: J Pharmacol Exp Ther. 2010 Apr; 333(1):152-60. Related CAS#: 957118-49-9 (free base); 957116-20-0 (HCl) Description:MK-3207 is a novel, potent and orally bioactive CGRP (Calcitonin generelated peptide) receptor antagonist with IC50 and Kiof 0.12 nM and0.022 nM, it is highly selective versus human AM1, AM2, CTR, andAMY3. MK 3207 exhibits significantly higher affinity for both native andrecombinant human CGRP receptor, as well as rhesus monkey CGRP receptorwith Ki of 24 pM, ca.24 pM and 22 pM, respectively, as compared to CGRPreceptors from other species, including canine and rodent (Ki values ofca.10 nM). Description: References: J Pharmacol Exp Ther. 2010 Apr; 333(1):152-60. References: Related CAS#: 957118-49-9 (free base); 957116-20-0 (HCl)
Molecular Weight (MW)	557.60
Formula	C31H29F2N5O3
CAS No.	957118-49-9 (free base)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: >= 100 mg/mL
	Water: N/A
	Ethanol: N/A
Solubility (In vivo)	1% DMSO+30% polyethylene glycol+1% Tween 80: 30mg/mL
Synonyms	MK-3207 HCl; MK3207; MK 3207

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 mg

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Delivery expected until 9/4/2025

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