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ISLATRAVIR

ISLATRAVIR

Item no.	V4389-10mg
Manufacturer	InvivoChem LLC
CASRN	865363-93-5
Amount	10 mg
Quantity options	100 mg 1 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4389CAS #:865363-93-5 Purity >=98% Description: Islatravir (also known as MK-8591) is a novel and potent anti-HIV-1 agent which acts as a nucleoside reverse transcriptase inhibitor with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. It has the potential use as an antiviral drug for the treatment of HIV infection. References: Chem Rec. 2006; 6(3):133-43.
	Name: Islatravir CAS#: 865363-93-5 Chemical Formula: C12H12FN5O3 Exact Mass: 293.0924 Molecular Weight: 293.2584 Elemental Analysis: C, 49.15; H, 4.12; F, 6.48; N, 23.88; O, 16.37
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: MK-8591; MK 8591; MK8591; EFdA IUPAC/Chemical Name: (2R, 3S, 5R)-5-(6-amino-2-fluoro-9H-purin-9-yl)-2-ethynyl-2-(hydroxymethyl)tetrahydrofuran-3-ol InChi Key: IKKXOSBHLYMWAE-QRPMWFLTSA-N InChi Code: InChI=1S/C12H12FN5O3/c1-2-12(4-19)6(20)3-7(21-12)18-5-15-8-9(14)16-11(13)17-10(8)18/h1, 5-7, 19-20H, 3-4H2, (H2, 14, 16, 17)/t6-, 7+, 12+/m0/s1 SMILES Code: NC1=C(N=CN2[CH]3C[CH]([C](O3)(C#C)CO)O)C2=NC(F)=N1

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Amount: 10 mg

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Delivery expected until 9/4/2025

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