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Vortioxetine (AA21004)

Vortioxetine (AA21004)

Item no.	V4425-500mg
Manufacturer	InvivoChem LLC
CASRN	508233-74-7
Amount	500 mg
Quantity options	100 mg 10 mg 1 g 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4425CAS #:508233-74-7 (free base)Purity >=98% Description: Vortioxetine (formerly known as Lu AA21004) is a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. Vortioxetine is an atypical antidepressant whichwas approved in 2013 by the FDA for the treatment of major depressive disorder (MDD) in adults. Vortioxetine is a so-called 'serotonin modulator and stimulator'. References: J Med Chem. 2011 May 12; 54(9):3206-21; J Pharmacol Exp Ther. 2012 Mar; 340(3):666-75. Related CAS: 960203-27-4 (HBr); 1253056-29-9 (lactate)
Molecular Weight (MW)	298.45
Formula	C18H22N2S.HBr
CAS No.	960203-27-4 (HBr); 508233-74-7 (free base); 1253056-29-9 (lactate)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 50 mg/mL
	Water:< 1 mg/mL
	Ethanol: N/A
Solubility (In vivo)	15% Captisol, pH 9: 10 mg/mL
Synonyms	LuAA21004, Lu-AA21004, Lu AA21004, AA21004, AA21004; AA-21004; AA 21004; Vortioxetine, vortioxetine hydrobromide, Brintellix
SMILES Code	CC1=CC=C(SC2=CC=CC=C2N3CCNCC3)C(C)=C1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 500 mg

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Delivery expected until 9/4/2025

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