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pf-3893787

pf-3893787

Item no.	V4464-10mg
Manufacturer	InvivoChem LLC
CASRN	943057-12-3 (free)
Amount	10 mg
Quantity options	25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4464CAS #:943057-12-3 (free)Purity >=98% Description: PF-3893787 (also known as Adriforant; ZPL-3893787; PF-3893787 and ZPL-389) is a novel and potent histamine H4 receptor antagonist with Ki of 2.4 nM and it is also a functional antagonist with Ki of 1.56 nM. Adriforant shows an excellent in vitro profile that warrants their further investigation in relevant models of human disease. Histamine H4 receptor (H4R) has become a promising target for immuno-inflammatory diseases, such as allergic rhinitis, asthma or dermal allergies. References: Bioorg Med Chem Lett. 2011 Nov 1; 21(21):6596-602. Related CAS: 2096455-90-0 (PF-3893787 hydrochloride)
	Name: PF-3893787/Adriforant CAS#: 943057-12-3 Chemical Formula: C13H22N6 Exact Mass: 262.19059 Molecular Weight: 262.36 Elemental Analysis: C, 59.51; H, 8.45; N, 32.03
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: PF-3893787; PF3893787; PF 3893787; Adriforant; ZPL-3893787; ZPL3893787; ZPL 3893787; ZPL-389; ZPL 389; ZPL389; PF-03893787; PF03893787; PF 03893787; IUPAC/Chemical Name: (R)-N4-(cyclopropylmethyl)-6-(3-(methylamino)pyrrolidin-1-yl)pyrimidine-2, 4-diamine InChi Key: ISBHYKVAFKTATD-SNVBAGLBSA-N InChi Code: InChI=1S/C13H22N6/c1-15-10-4-5-19(8-10)12-6-11(17-13(14)18-12)16-7-9-2-3-9/h6, 9-10, 15H, 2-5, 7-8H2, 1H3, (H3, 14, 16, 17, 18)/t10-/m1/s1 SMILES Code: NC1=NC(N2CC[CH](NC)C2)=CC(NCC3CC3)=N1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 10 mg

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Delivery expected until 9/4/2025

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