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Bumetanide

Bumetanide

Item no.	V4488-2g
Manufacturer	InvivoChem LLC
CASRN	28395-03-1
Amount	2 g
Quantity options	1 g 250 mg 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4488CAS #:28395-03-1 Purity >=98% Description: Bumetanide (also known as Ro 10-6338; PF-1593) is a novel and potent inhibitor of Na(+)-K(+)-2Cl(-) co-transporter (NKCC) with an IC50 of 0.6 uM. Bumetanide is a loop diuretic belonging to the sulfamyl category and is used to treat heart failure, and is often used in people in whom high doses of furosemide are ineffective. Bumetanide is almost completely absorbed (80%), and the absorption is not altered when it is taken with food. It is said to be a more predictable diuretic, meaning that the predictable absorption is reflected in a more predictable effect. References: 1986 Jan 14; 134(1):326-31.
	Name: Bumetanide CAS#: 28395-03-1 Chemical Formula: C17H20N2O5S Exact Mass: 364.10929 Molecular Weight: 364.4161 Elemental Analysis: C, 56.03; H, 5.53; N, 7.69; O, 21.95; S, 8.80
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: PF 1593, PF-1593, PF1593; Ro 10-6338; Ro-10-6338; Ro 10 6338; Trade names: Bumex or Burinex; IUPAC/Chemical Name: 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid InChi Key: MAEIEVLCKWDQJH-UHFFFAOYSA-N InChi Code: InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18, 22)23)16(14)24-13-7-5-4-6-8-13/h4-8, 10-11, 19H, 2-3, 9H2, 1H3, (H, 20, 21)(H2, 18, 22, 23) SMILES Code: O=C(O)C1=CC(S(=O)(N)=O)=C(OC2=CC=CC=C2)C(NCCCC)=C1

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Amount: 2 g

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