« Back
Home /
JNJ-10229570

JNJ-10229570

Item no.	V4507-100mg
Manufacturer	InvivoChem LLC
CASRN	524923-88-4
Amount	100 mg
Quantity options	10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4507CAS #:524923-88-4Purity >=98% Description: JNJ-10229570 is a novel, potent and selective antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R) with the potential to treat primary human sebaceous cells and for the treatment of acne and other sebaceous gland pathologies. JNJ-10229570 inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-alpha-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively. References: J Dermatol Sci. 2011 Jul; 63(1):23-32.
	Name: JNJ-10229570 CAS#: 524923-88-4 Chemical Formula: C22H19N3O2S Exact Mass: 389.1198 Molecular Weight: 389.47 Elemental Analysis: C, 67.84; H, 4.92; N, 10.79; O, 8.22; S, 8.23
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: JNJ-10229570; JNJ10229570; JNJ 10229570; UNII-N9IX402L35. IUPAC/Chemical Name: Benzenamine, N-(2, 3-bis(2-methoxyphenyl)-1, 2, 4-thiadiazol-5(2H)-ylidene)- InChi Key: XTHRTBCPBWJYRO-GHVJWSGMSA-N InChi Code: InChI=1S/C22H19N3O2S/c1-26-19-14-8-6-12-17(19)21-24-22(23-16-10-4-3-5-11-16)28-25(21)18-13-7-9-15-20(18)27-2/h3-15H, 1-2H3/b23-22+ SMILES Code: COC1=CC=CC=C1C2=N/C(SN2C3=CC=CC=C3OC)=N\C4=CC=CC=C4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 mg

available

Delivery expected until 9/4/2025

Express Delivery: Save 8 days

Compare

Add to wishlist

Get an offer