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gdc-0339

gdc-0339

Item no.	V4527-25mg
Manufacturer	InvivoChem LLC
CASRN	1428569-85-0
Amount	25 mg
Quantity options	100 mg 10 mg 1 mg 250 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4527CAS #:1428569-85-0Purity >=98% Description: GDC-0339 is a novel, orally bioavailable, potent and selective small molecule pan-Pim kinase inhibitor with IC50 of 43.6 nM for BaF3 PIM1. GDC-0339 was discovered as a potential treatment of multiple myeloma. References: Drug Metab Dispos. 2017 Oct; 45(10):1084-1092.
	Name: GDC-0339 CAS#: 1428569-85-0 Chemical Formula: C20H22F3N7OS Exact Mass: 465.1559 Molecular Weight: 465.49 Elemental Analysis: C, 51.60; H, 4.76; F, 12.24; N, 21.06; O, 3.44; S, 6.89
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: GDC-0339; GDC 0339; GDC0339 IUPAC/Chemical Name: 5-Amino-N-(5-((4R, 5R)-4-amino-5-fluoroazepan-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(2, 6-difluorophenyl)thiazole-4-carboxamide InChi Key: NHXVGMQFCYBLTL-ZWNOBZJWSA-N InChi Code: InChI=1S/C20H22F3N7OS/c1-29-20(30-7-5-10(21)13(24)6-8-30)14(9-26-29)27-18(31)16-17(25)32-19(28-16)15-11(22)3-2-4-12(15)23/h2-4, 9-10, 13H, 5-8, 24-25H2, 1H3, (H, 27, 31)/t10-, 13-/m1/s1 SMILES Code: O=C(C1=C(N)SC(C2=C(F)C=CC=C2F)=N1)NC3=C(N4CC[CH](N)[CH](F)CC4)N(C)N=C3

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Amount: 25 mg

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Delivery expected until 9/4/2025

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