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TAK-593

TAK-593

Item no.	V4585-25mg
Manufacturer	InvivoChem LLC
CASRN	1005780-62-0
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4585CAS #:1005780-62-0Purity >=98% Description: TAK-593 is a novel, orally bioavailable and potent small-molecule receptor of VEGFR and PDGFR with IC50s of 3.2, 0.95, 1.1, 4.3 and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRalpha and PDFGRbeta, respectively. TAK-593 has potential antineoplastic activity. TAK-593 selectively binds to and inhibits VEGFR and PDGFR, which may result in the inhibition of angiogenesis and tumor cell proliferation. References: Bioorg Med Chem. 2013 Apr 15; 21(8):2333-2345.; Cancer Sci. 2013 Apr; 104(4):486-94.
	Name: TAK-593 CAS#: 1005780-62-0 Chemical Formula: C23H23N7O3 Exact Mass: 445.18624 Molecular Weight: 445.47382 Elemental Analysis: C, 62.01; H, 5.20; N, 22.01; O, 10.77
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: TAK-593, TAK593, TAK 593 IUPAC/Chemical Name: N-(5-((2-(cyclopropanecarboxamido)imidazo[1, 2-b]pyridazin-6-yl)oxy)-2-methylphenyl)-1, 3-dimethyl-1H-pyrazole-5-carboxamide InChi Key: DZFZXPPHBWCXPQ-UHFFFAOYSA-N InChi Code: InChI=1S/C23H23N7O3/c1-13-4-7-16(11-17(13)24-23(32)18-10-14(2)27-29(18)3)33-21-9-8-20-25-19(12-30(20)28-21)26-22(31)15-5-6-15/h4, 7-12, 15H, 5-6H2, 1-3H3, (H, 24, 32)(H, 26, 31) SMILES Code: O=C(C1=CC(C)=NN1C)NC2=CC(OC3=NN4C(C=C3)=NC(NC(C5CC5)=O)=C4)=CC=C2C

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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Delivery expected until 9/4/2025

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