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Description: Eprobemide is a potent non-competitive reversible inhibitor of monoamine oxidase A, which was used as an antidepressant in Russia (under the trade name Befol). It exhibits selective action on serotonin deamination. Eprobemide differs from moclobemide only in the linker that connects the morpholine fragment with the chlorobenzamide — moclobemide has two carbon atoms while eprobemide has three. Its registration was cancelled on December 30, 2003.
References: Pharmaceutical Chemistry Journal, 2004 Jun; 38(7): 381-384.
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