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nvp-bag956

nvp-bag956

Item no.	V4659-250mg
Manufacturer	InvivoChem LLC
CASRN	853910-02-8
Amount	250 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4659CAS #:853910-02-8Purity >=98% Description: NVP-BAG956 (also known as BAG 956) is a novel, potent and ATP-competitive PI3K inhibitor with IC50 values of 34, 56, 112 and 444 nM for PI3Kdelta, PI3Kalpha, PI3Kgamma and PI3Kbeta, respectively. NVP-BAG956 has been shown to inhibit cellular AKT phosphorylation at Thr308. BAG 956 also blocks cell proliferation and causes arrest in the G1 phase of the cell cycle. BAG 956 has been shown to slow tumor progression in mouse xenograft models. References: Mol Cancer Res. 2009 Apr; 7(4):601-13.
	Name: NVP-BAG-956 CAS#: 853910-02-8 Chemical Formula: C24H35ClN2O2 Exact Mass: 418.23871 Molecular Weight: 419.0 Elemental Analysis: C, 68.80; H, 8.42; Cl, 8.46; N, 6.69; O, 7.64
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: NVP-BAG956; NVP-BAG-956; NVP-BAG 956; BAG-956; BAG 956; BAG956; IUPAC/Chemical Name: Benzamide, 2-chloro-5-(3-((3-hydroxypropyl)amino)propyl)-N-(tricyclo(3.3.1.13, 7)dec-1-ylmethyl)- InChi Key: HSQAARMBHJCUOK-UHFFFAOYSA-N InChi Code: InChI=1S/C24H35ClN2O2/c25-22-5-4-17(3-1-6-26-7-2-8-28)12-21(22)23(29)27-16-24-13-18-9-19(14-24)11-20(10-18)15-24/h4-5, 12, 18-20, 26, 28H, 1-3, 6-11, 13-16H2, (H, 27, 29) SMILES Code: c1cc(c(cc1CCCNCCCO)C(=O)NCC23CC4CC(C2)CC(C4)C3)Cl

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Amount: 250 mg

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Delivery expected until 9/4/2025

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