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Dimethylcurcumin

Dimethylcurcumin

Item no.	V4725-50mg
Manufacturer	InvivoChem LLC
CASRN	52328-98-0
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4725CAS #:52328-98-0Purity >=98% Description: Dimethylcurcumin (formerly known as ASC-J9; GO-Y025) is an androgen receptor (AR) degradation enhancer that effectively suppresses castration resistant prostate cancer cell proliferation and invasion. Dimethylcurcumin suppresses renal cell carcinoma progression by targeting an androgen receptor-dependent HIF2alpha/VEGF signaling pathway.ASC-J9 treatment enhanced BCG efficacy to suppress bladder cancer cell proliferation via increasing the recruitment of monocytes/macrophages that involved the promotion of BCG attachment/internalization to the bladder cancer cells through increased integrin-alpha5beta1 expression and IL6 release. References: Neoplasia. 2012 Jan; 14(1):74-83.; Nat Med. 2007 Mar; 13(3):348-53.; Biochem Biophys Res Commun. 2017 Apr 15; 485(4):746-752.
	Name: Dimethylcurcumin (ASC-J9) CAS#: 52328-98-0 Chemical Formula: C23H24O6 Exact Mass: 396.1573 Molecular Weight: 396.439 Elemental Analysis: C, 69.68; H, 6.10; O, 24.21
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: ASC-J9; ASC-J-9; ASC J9; GO-Y025; GO-Y 025; GO Y025; IUPAC/Chemical Name: (1E, 4Z, 6E)-1, 7-bis(3, 4-dimethoxyphenyl)-5-hydroxyhepta-1, 4, 6-trien-3-one InChi Key: ZMGUKFHHNQMKJI-CIOHCNBKSA-N InChi Code: InChI=1S/C23H24O6/c1-26-20-11-7-16(13-22(20)28-3)5-9-18(24)15-19(25)10-6-17-8-12-21(27-2)23(14-17)29-4/h5-15, 24H, 1-4H3/b9-5+, 10-6+, 18-15- SMILES Code: O=C(/C=C(O)/C=C/C1=CC=C(OC)C(OC)=C1)/C=C/C2=CC=C(OC)C(OC)=C2

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Amount: 50 mg

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Delivery expected until 12/4/2025

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