balamapimod

InvivoChem Cat #:V4732CAS #:863029-99-6Purity >=98%

Description: Balamapimod (formerly also known as MKI-833) is a novel, potent, and reversible Ras/Raf/MEK inhibitor. Balamapimod may be potentially useful for the treatment cancer. In addition, Balamapimod may be also useful for the treatment of stroke, osteoporosis, rheumatoid arthritis and other inflammatory disorders, as well as polycystic kidney disease and colonic polyps.

References: US20170020964A1.

-20C for 3 years in powder form

Synonym: MKI-833; MKI 833; MKI833
IUPAC/Chemical Name: 4-((3-chloro-4-((1-methyl-1H-imidazol-2-yl)thio)phenyl)amino)-6-methoxy-7-(4-(pyrrolidin-1-yl)piperidin-1-yl)quinoline-3-carbonitrile
InChi Key: CVAKNHIXTWLGJO-UHFFFAOYSA-N
InChi Code: InChI=1S/C30H32ClN7OS/c1-36-14-9-33-30(36)40-28-6-5-21(15-24(28)31)35-29-20(18-32)19-34-25-17-26(27(39-2)16-23(25)29)38-12-7-22(8-13-38)37-10-3-4-11-37/h5-6, 9, 14-17, 19, 22H, 3-4, 7-8, 10-13H2, 1-2H3, (H, 34, 35)
SMILES Code: N#CC1=C(NC2=CC=C(SC3=NC=CN3C)C(Cl)=C2)C4=CC(OC)=C(N5CCC(N6CCCC6)CC5)C=C4N=C1