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AM-92016 HCl

AM-92016 HCl

Item no.	V4822-500mg
Manufacturer	InvivoChem LLC
CASRN	133229-11-5
Amount	500 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4822CAS #:133229-11-5 (HCl)Purity >=98% Description: AM-92016 HCl, the hydrochloride salt of AM-92016 (an oxypropanolamine analog of sotalol), is a novel, potent and specific IK inhibitor. It has bpotential Class III anti-arrhythmic properties in-vitro at concentrations showing 1000 times more potency than sotalol. AM 92016 exhibited proarrhythmic rather than antiarrhythmic activity when administered in-vivo to either guinea-pigs or pigs.AM-92016 (hydrochloride) delays rectifier potassium channel (IK), repolarizes the membrane thereby restricting the duration of the nerve impulse. AM 92016 (hydrochloride) prolongs cardiac action potential duration in guinea-pig and rabbit isolated ventricular cells with an IC50 of 30 nM. References: Br J Pharmacol. 1992 Aug; 106(4):958-65. Related CAS : 133229-11-5 (HCl); 133229-23-9 (free base)
	Name: AM-92016 HCl CAS#: 133229-11-5 (HCl) Chemical Formula: C19H25Cl3N2O4S Exact Mass: Molecular Weight: 483.829 Elemental Analysis: C, 47.17; H, 5.21; Cl, 21.98; N, 5.79; O, 13.23; S, 6.63
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: AM92016 HCl; AM-92016 hydrochloride; AM-92016 HCl; AM 92016 HCl; IUPAC/Chemical Name: N-(4-(3-((3, 4-dichlorophenethyl)(methyl)amino)-2-hydroxypropoxy)phenyl)methanesulfonamide hydrochloride InChi Key: TXOARFPCQOBODS-UHFFFAOYSA-N InChi Code: InChI=1S/C19H24Cl2N2O4S.ClH/c1-23(10-9-14-3-8-18(20)19(21)11-14)12-16(24)13-27-17-6-4-15(5-7-17)22-28(2, 25)26; /h3-8, 11, 16, 22, 24H, 9-10, 12-13H2, 1-2H3; 1H SMILES Code: OC(CN(C)CCC1=CC=C(Cl)C(Cl)=C1)COC2=CC=C(NS(=O)(C)=O)C=C2.[H]Cl

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Amount: 500 mg

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Delivery expected until 9/4/2025

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