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myriocin

myriocin

Item no.	V4827-250mg
Manufacturer	InvivoChem LLC
CASRN	35891-70-4
Amount	250 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4827CAS #:35891-70-4Purity >=98% Description: Myriocin (formerly also known as antibiotic ISP-1 and thermozymocidin), a fungal metabolite and an atypical amino acid and an antibiotic isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a novel and potent inhibitor of serine-palmitoyl-transferase (SPT) which is a key enzyme in de novo synthesis of sphingolipids. Myriocin strongly suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 ug/mL for inhibiting HCV infection. Myriocin, also known as antibiotic ISP-1 and thermozymocidin, References: J Infect Dis. 2008 Oct 1; 198(7):1091-3.
	Name: Myriocin CAS#: 35891-70-4 Chemical Formula: C21H39NO6 Exact Mass: 401.2777 Molecular Weight: 401.54 Elemental Analysis: C, 62.82; H, 9.79; N, 3.49; O, 23.91
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: Thermozymocidin; ISP-I; ISP I; ISP1 IUPAC/Chemical Name: (2R, 3R, 4S, E)-2-amino-3, 4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid InChi Key: ZZIKIHCNFWXKDY-ANSFIGKPSA-N InChi Code: InChI=1S/C21H39NO6/c1-2-3-4-10-13-17(24)14-11-8-6-5-7-9-12-15-18(25)19(26)21(22, 16-23)20(27)28/h9, 12, 18-19, 23, 25-26H, 2-8, 10-11, 13-16, 22H2, 1H3, (H, 27, 28)/b12-9+/t18-, 19-, 21+/m0/s1 SMILES Code: CCCCCCC(CCCCCC/C=C/C[CH](O)[CH](O)[C](CO)(N)C(O)=O)=O

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 10/2/2025

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