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Description: LY 178002 is a novel and potent inhibitor of 5-lipoxygenase, phospholipase A2 with IC50 of 0.6 uM for 5-1ipoxygenase, it inhibits cellular production of LTB4 by human polymorphonuclear leukocytes, and shows relatively weak inhibition on cyclooxygenase.
References: Agents Actions. 1989 Jun; 27(3-4):300-2.
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