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Description: Bifluranol (formerly also known as BX-341; traded name Prostarex), a novel fluorinated bibenzyl anti-androgen, is a potent and synthetic nonsteroidal estrogen of the stilbestrol calss related to diethylstilbestrol that has been used as an antiandrogen in the United Kingdom in the treatment of benign prostatic hyperplasia. It exerts functional antiandrogen effects by binding to and activating the estrogen receptor in the pituitary gland, consequently suppressing the secretion of luteinizing hormone (and hence acting as an antigonadotropin) and thereby reducing gonadal androgen production and systemic androgen levels.
References: J Pharm Pharmacol. 1981 May; 33(5):297-301.
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
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