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Description: Lanosterol, a naturally-occurring triterpenoid derivative, is a key imtermediate in the biosynthesis of Cholesterol. Lanosterol is metabolized to Cholesterol and Cucurbitacins. Lanosterol is a naturally-occurring sterol and biosynthetic precursor of several animal, fungal, and protozoan steroids, including cholesterol and ergosterol. Defects in the processing of lanosterol contribute to a wide variety of disorders, including the formation of cataracts. Similarly, certain fungicides act by blocking lanosterol processing by fungi.
References: Angew Chem Int Ed Engl. 2015 Jul 20; 54(30):8693-6.
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