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Dexpramipexole HCl

Dexpramipexole HCl

Item no.	V4976-25mg
Manufacturer	InvivoChem LLC
CASRN	104632-27-1
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4976CAS #:104632-27-1 (HCl)Purity >=98% Description: Dexpramipexole (also known as KNS-760704, R-(+)-Pramipexole and (R)-Pramipexole), an enantiomer of pramipexole, is a dopamine agonist of the non-ergoline class with the potential for the treatment of amyotrophic lateral sclerosis (ALS) (also known as Lou Gehrig’s disease). It consistently and markedly lowering peripheral blood eosinophils. Dexpramipexole is a low molecular weight, water-soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics, and has been shown to be well tolerated in human subject testing. KNS-760704 is the enantiomer of pramipexole, and has been shown to improve mitochondrial function and to confer significant cellular protection in neurons under stress. References: Amyotroph Lateral Scler Frontotemporal Degener. 2013 Jan; 14(1):44-51.; Brain Res. 2012 Mar 29; 1446:1-11. Related CAS #: 104632-27-1 (HCl) 104632-28-2 (free base) 908244-04-2 (HCl hydrate)
	Name: Dexpramipexole HCl CAS#: 104632-27-1 (HCl) Chemical Formula: C10H19Cl2N3S Exact Mass: Molecular Weight: 284.243 Elemental Analysis: C, 42.26; H, 6.74; Cl, 24.94; N, 14.78; S, 11.28
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: Dexpramipexole dihydrochloride; KNS-760704; KNS760704; KNS 760704; R-Pramipexole; IUPAC/Chemical Name: (6R)-6-N-Propyl-4, 5, 6, 7-tetrahydro-1, 3-benzothiazole-2, 6-diamine; hydrate dihydrochloride InChi Key: OVFMIJINNIJYKB-YQFADDPSSA-N InChi Code: InChI=1S/C10H17N3S.2ClH/c1-2-4-10(12)5-3-7-8(6-10)14-9(11)13-7; ; /h2-6, 12H2, 1H3, (H2, 11, 13); 2*1H/t10-; ; /m1../s1 SMILES Code: NC1=NC(CC[C](N)(CCC)C2)=C2S1.[H]Cl.[H]Cl

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Amount: 25 mg

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Delivery expected until 9/4/2025

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