Comparison

Talipexole HCl

Item no. V4978-250mg
Manufacturer InvivoChem LLC
CASRN 36085-73-1
Amount 250 mg
Quantity options 100 mg 10 mg 25 mg 500 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V4978CAS #:36085-73-1Purity >=98%

Description: Talipexole dihydrochloride (also known as B-HT920, Domnin, B-HT-920 dihydrochloride) is a novel and potent dopamine D2 receptor agonist, alpha2-adrenoceptor agonist and 5-HT3 receptor antagonist, which displays anti-parkinsonian activity. Talipexole is marketed as a treatment for Parkinson's Disease in Japan by Boehringer Ingelheim; it was introduced in 1996. As of December 2014 it was not approved for marketing in the US nor in Europe. Talipexole is a D2 dopamine receptor agonist and interacts both pre- and post-synaptic receptors. It also is an alpha2-adrenergic agonist. The main side effects are drowsiness, dizziness, hallucinations and minor gastrointestinal complaints. In 2008 the Japanese Ministry of Health, Labour, and Welfare mandated that Boehringer add a warning to the label concerning the risk of sudden onset of sleep.

References: Gen.Pharmacol. (1999)32 29.

Related CAS #: 36085-73-1 (2HCl); 101626-70-4 (free base)


Talipexole HCl

Name: Talipexole HCl
CAS#: 36085-73-1
Chemical Formula: C10H17Cl2N3S
Exact Mass:
Molecular Weight: 282.227
Elemental Analysis: C, 42.56; H, 6.07; Cl, 25.12; N, 14.89; S, 11.36
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Technical Information
Synonym: B-HT 920, B-HT-920, B-HT920, Talipexole HCl, Talipexole dihydrochloride, Domnin
IUPAC/Chemical Name: 6-Allyl-2-amino-5, 6, 7, 8-tetrahydro-4H-thiazolo(4, 5-d)azepine dihydrochloride
InChi Key: DPQAXNSOFFYKDS-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H15N3S.2ClH/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8; ; /h2H, 1, 3-7H2, (H2, 11, 12); 2*1H
SMILES Code: NC(S1)=NC2=C1CCN(CC=C)CC2.[H]Cl.[H]Cl

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 mg
Available: In stock
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