Comparison

fiacitabine

Item no. V5084-25mg
Manufacturer InvivoChem LLC
CASRN 69123-90-6
Amount 25 mg
Quantity options 100 mg 10 mg 1 mg 250 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V5084CAS #:69123-90-6Purity >=98%

Description: Fiacitabine(also known as NSC 382097; DRG-0077) is a novel, potent and selective inhibitior of DNA replication of herpes simplex virus(HSV) with IC50 values of 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively. Fiacitabine is a pyrimidine nucleoside analog reported to elicit potent anti-VZV activity both in vitro and in vivo. Fiacitabine has potent antiviral activity in vivo against herpes simplex virus types 1 and 2 and cytomegalovirus. Fiacitabine is therapeutically superior to ara-A for the treatment of varicella-zoster virus infections in immunosuppressed subjects.

References: J Biol Chem. 1982 Oct 25; 257(20):11879-82.

Fiacitabine

Name: Fiacitabine
CAS#: 69123-90-6
Chemical Formula: C9H11FIN3O4
Exact Mass: 370.9778
Molecular Weight: 371.1069
Elemental Analysis: C, 29.13; H, 2.99; F, 5.12; I, 34.20; N, 11.32; O, 17.24
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Technical Information
Synonym: DRG-0077; DRG 0077; DRG0077; FIAC; FOAC; NSC 382097; NSC-382097; NSC382097; Fluoroiodoaracytidine. Fluorviodoaracytidine.
Chemical Name: 4-amino-1-((2R, 3S, 4R, 5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one
InChi Key: GIMSJJHKKXRFGV-BYPJNBLXSA-N
InChi Code: InChI=1S/C9H11FIN3O4/c10-5-6(16)4(2-15)18-8(5)14-1-3(11)7(12)13-9(14)17/h1, 4-6, 8, 15-16H, 2H2, (H2, 12, 13, 17)/t4-, 5+, 6-, 8-/m1/s1
SMILES Code: O=C1N=C(N)C(I)=CN1[CH]2[CH](F)[CH]([CH](CO)O2)O

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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