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Description: Uramustine (also known as Uracil mustard) is a novel, potent and orally bioactive DNA alkylating agent with antineoplastic activities, it is effective in the treatment of lymphosarcoma, chronic lymphatic leukaemia, and thrombocythemia.
References: J Med Chem. 2002 Aug 15; 45(17):3630-3638.
Synonym: Uracil mustard; Uramustine; Demethyldopan, Desmethyldopan, Uracilmostaza, Uracillost, Uramustin, Nordopan, Chlorethaminacil, Aminouracil mustard, Uramustina, Uramustinum
Chemical Name: 2, 4(1H, 3H)-Pyrimidinedione, 5-(bis(2-chloroethyl)amino)-InChi Key: IDPUKCWIGUEADI-UHFFFAOYSA-NInChi Code: InChI=1S/C8H11Cl2N3O2/c9-1-3-13(4-2-10)6-5-11-8(15)12-7(6)14/h5H, 1-4H2, (H2, 11, 12, 14, 15)SMILES Code: O=C1NC(C(N(CCCl)CCCl)=CN1)=O
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