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PLX-5622

PLX-5622

Item no.	V5140-25mg
Manufacturer	InvivoChem LLC
CASRN	1303420-67-8
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5140CAS #:1303420-67-8Purity >=98% Description: PLX5622 is a novel and highly selective CNS-penetrant CSF1R inhibitor, that has the potential to be used for extended and specific microglial elimination, preceding and during pathology development. Many risk genes for the development of Alzheimer's disease (AD) are exclusively or highly expressed in myeloid cells. Microglia are dependent on colony-stimulating factor 1 receptor (CSF1R) signaling for their survival. References: Nat Commun. 2019 Aug 21; 10(1):3758.
	Name: PLX5622 CAS#: 1303420-67-8 Chemical Formula: C21H19F2N5O Exact Mass: 395.1558 Molecular Weight: 395.4138 Elemental Analysis: C, 63.79; H, 4.84; F, 9.61; N, 17.71; O, 4.05
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: PLX5622 free base; PLX-5622 free base; PLX 5622 free base; PLX5622; PLX-5622; PLX 5622; Chemical Name: 6-fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2, 3-b]pyridin-3-yl)methyl)pyridin-2-amine SMILES Code: CC1=CN=C2C(C(CC3=C(F)N=C(NCC4=CC(F)=CN=C4OC)C=C3)=CN2)=C1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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Delivery expected until 11/6/2025

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