Cefmenoxime HCl (SCE-1365)

InvivoChem Cat #:V5181CAS #:75738-58-8Purity >=98%

Description: Cefmenoxime HCl (SCE1365), the hydrochloride salt of Cefmenoxime, is a third-generation cephalosporin class of antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms, is a potent inhibitor of Enterobacteriaceae, and is highly resistant to hydrolysis by beta-lactamases. The bactericidal activity of cefmenoxime results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).The drug has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.

References: Ann Pharmacother. 1994 Mar; 28(3):384-9.; Jpn J Antibiot. 1995 May; 48(5):602-9.

Related CAS: 65085-01-0 (Cefmenoxime; A50912; A 50912; A-50912; AB 50912)

-20C for 3 years in powder form

Synonym: Cefmenoxime Hydrochloride; SCE 1365 hydrochloride; AB 50912 hemihydrochloride; EINECS 278-299-4; SCE1365; Hydrochloride, Cefmenoxime; SCE 1365; SCE-1365;
Chemical Name: 7-[[(2E)-2-(2-amino-1, 3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; hydrochloride
InChi Key: MPTNDTIREFCQLK-RGZOMKIGSA-N
InChi Code: InChI=1S/2C16H17N9O5S3.ClH/c2*1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7; /h2*5, 9, 13H, 3-4H2, 1-2H3, (H2, 17, 18)(H, 19, 26)(H, 28, 29); 1H/b2*21-8+;
SMILES Code: CN1N=NN=C1SCC2=C(N3C(=O)C(C3SC2)NC(=O)/C(=N/OC)/C4=CSC(=N4)N)C(=O)O.CN1N=NN=C1SCC2=C(N3C(=O)C(C3SC2)NC(=O)/C(=N/OC)/C4=CSC(=N4)N)C(=O)O.Cl