Rifabutin (Ansamycin; LM-427)

InvivoChem Cat #:V5191CAS #:72559-06-9Purity >=98%

Description: Rifabutin (also known as Ansamycin) is a semisynthetic ansamycin and broad-spectrum antibiotic with potent antimycobacterial properties. Rifabutin is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.

References: Antimicrob Agents Chemother. 2012 Aug; 56(8):4303-9.

-20C for 3 years in powder form

Synonym: Ansamycin; Rifabutin; LM-427; LM 427; LM427; Mycobutin; Rifabutina;
Chemical Name: Rifamycin XIV, 1', 4-didehydro-1-deoxy-1, 4-dihydro-5'-(2-methylpropyl)-1-oxo-
InChi Key: ATEBXHFBFRCZMA-NYGPAKPVSA-N
InChi Code: InChI=1S/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10, 61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15, 20, 22-23, 25-27, 30, 37-38, 41, 49, 52-54H, 16-19, 21H2, 1-11H3, (H, 47, 57)/b13-12+, 20-15+, 24-14+/t23-, 25+, 26+, 27+, 30-, 37-, 38+, 41+, 45-/m0/s1
SMILES Code: O=C1c2c(O)c(C)c3c(C4=O)c2C5=NC6(CCN(CC(C)C)CC6)NC5=C1NC(/C(C)=C/C=C/[CH]([CH](O)[CH]([CH](O)[CH]([CH]([CH](C)[CH](OC)/C=C/O[C]4(O3)C)OC(C)=O)C)C)C)=O