Comparison

CID-16020046

Item no. V5220-50mg
Manufacturer InvivoChem LLC
CASRN 834903-43-4
Amount 50 mg
Quantity options 100 mg 10 mg 250 mg 25 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V5220CAS #:834903-43-4 Purity >=98%

Description: CID-16020046 is a novel, potent and selective GPR55 (LPI receptor) antagonist / inverse agonist which inhibits GPR55 constitutive activity with IC50 of 0.15 uM. GPR55 is a G protein-coupled receptor that is weakly activated by some cannabinoids at nM concentrations. CID16020046 has been shown to block GPR55-mediated endothelial wound healing and reverse LPI-inhibited platelet aggregation. The G protein-coupled receptor 55 (GPR55) is a lysophosphatidylinositol (LPI) receptor that is also responsive to certain cannabinoids. Although GPR55 has been implicated in several (patho)physiologic functions, its role remains enigmatic owing mainly to the lack of selective GPR55 antagonists.

References: J Pharmacol Exp Ther. 2013 Jul; 346(1):54-66.

CID-16020046

Name: CID16020046
CAS#: 834903-43-4
Chemical Formula: C25H19N3O4
Exact Mass: 425.1376
Molecular Weight: 425.44
Elemental Analysis: C, 70.58; H, 4.50; N, 9.88; O, 15.04
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Technical Information
Synonym: CID16020046; CID-16020046; CID 16020046.
Chemical Name: 4-[4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1, 4-dihydropyrrolo[3, 4-d]pyrazol-5-yl]benzoic acid
InChi Key: VGUQVYZXABOXCX-UHFFFAOYSA-N
InChi Code: InChI=1S/C25H19N3O4/c1-14-5-7-15(8-6-14)21-20-22(27-26-21)24(30)28(18-11-9-16(10-12-18)25(31)32)23(20)17-3-2-4-19(29)13-17/h2-13, 23, 29H, 1H3, (H, 26, 27)(H, 31, 32)
SMILES Code: O=C(O)C1=CC=C(N(C2=O)C(C3=CC=CC(O)=C3)C4=C2NN=C4C5=CC=C(C)C=C5)C=C1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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