dpq

Item no.	V5265-25mg
Manufacturer	InvivoChem LLC
CASRN	129075-73-6
Amount	25 mg
Quantity options	100 mg 10 mg 1 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5265CAS #:129075-73-6Purity >=98% Description: DPQ (also known as PARP Inhibitor III) is a novel and potent inhibitor of PARPs The poly(ADP-ribose) polymerases which inhibits PARP1 activity with an IC50 value of 40 nM. It is approximately 10-fold less potent against PARP2. DPQ can be used in either cells or in animals. The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. References: Current Medicinal Chemistry 19(23), 3907-3921 (2012).
	Formal Name: 3, 4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone CAS Number: 129075-73-6 Synonyms: PARP Inhibitor III Molecular Formula: C18H26N2O2 Formula Weight: 302.4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	SMILES: O=C1NCCC2=C(OCCCCN3CCCCC3)C=CC=C21 InChi Code: InChI=1S/C18H26N2O2/c21-18-16-7-6-8-17(15(16)9-10-19-18)22-14-5-4-13-20-11-2-1-3-12-20/h6-8H, 1-5, 9-14H2, (H, 19, 21) InChi Key: RVOUDNBEIXGHJY-UHFFFAOYSA-N

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Amount: 25 mg

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Delivery expected until 12/4/2025

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