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Iberdomide (CC-220)

Iberdomide (CC-220)

Item no.	V5268-100mg
Manufacturer	InvivoChem LLC
CASRN	1323403-33-3
Amount	100 mg
Quantity options	250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5268CAS #:1323403-33-3 Purity >=98% Description: Iberdomide (also known as CC-220) is a novel and potent cereblon (CRBN) modulator with an IC50 of 60 nM and can be potentially used for the treatment of systemic lupus erythematosus. Iberdomide significantly reduced Ikaros and Aiolos protein levels in B cells, T cells and monocytes. In SLE PBMC cultures, iberdomide inhibited anti-dsDNA and anti-phospholipid autoantibody production (IC50 ?10?nM). Reference: J Med Chem. 2017 Apr 20.
	Name: Iberdomide CAS#: 1323403-33-3 Chemical Formula: C25H27N3O5 Exact Mass: 449.1951 Molecular Weight: 449.5 Elemental Analysis: C, 66.80; H, 6.05; N, 9.35; O, 17.80
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: CC-220; CC220; CC 220. IUPAC/Chemical Name: (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2, 6-dione InChi Key: IXZOHGPZAQLIBH-NRFANRHFSA-N InChi Code: InChI=1S/C25H27N3O5/c29-23-9-8-21(24(30)26-23)28-15-20-19(25(28)31)2-1-3-22(20)33-16-18-6-4-17(5-7-18)14-27-10-12-32-13-11-27/h1-7, 21H, 8-16H2, (H, 26, 29, 30)/t21-/m0/s1 SMILES Code: O=C([CH](N(CC1=C2C=CC=C1OCC3=CC=C(CN4CCOCC4)C=C3)C2=O)CC5)NC5=O

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Amount: 100 mg

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